Study Finds Promise in Approved Drugs for Possible Covid-19 Treatment

A new paper published today in the journal Nature tested 75 over-the-counter prescription and development-stage drug compounds in human cells for activity against the novel coronavirus.

Two drug categories emerged as promising:

Protein translation inhibitors (including zotatifin and ternatin-4/plitidepsin), and drugs that modulate proteins inside the cell known as Sigma1 and Sigma2 receptors (including progesterone, PB28, PD-144418, hydroxychloroquine; the antipsychotic drugs haloperidol and cloperazine; siramesine, an antidepressant and anti-anxiety drug; and the antihistamines clemastine and cloperastine).

You can read the full study below.

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing