Oxford’s Coronavirus Vaccine Shows Promise

Early results suggest the vaccine did not prompt any serious side effects and elicited an immune response

Emily Mullin
Medium Coronavirus Blog

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A scientist working at the Oxford Vaccine Group’s laboratory facility at the Churchill Hospital in Oxford.
A scientist working at the Oxford Vaccine Group’s laboratory facility at the Churchill Hospital in Oxford. Photo: Steve Parsons/Pool/AFP/Getty Images

An experimental Covid-19 vaccine developed by researchers at the University of Oxford in the U.K. triggered an immune response in healthy adults and appears to have no dangerous side effects, according to research published Monday in the scientific journal The Lancet.

The study included 1,077 healthy people aged 18 to 55, about half of whom received the experimental Covid-19 vaccine. Ten of those people received two doses. The other half, a control group, received a meningitis vaccine that’s already on the market.

The Covid-19 vaccine seemed to spur an immune response, and in 32 out of 35 people, investigators found evidence of so-called “neutralizing” antibodies. These special antibodies are believed to be protective against the SARS-CoV-2 virus. They were still detectable about two months after one dose of the vaccine. Antibody levels were even higher in the ten participants who received a booster shot 28 days after the first one. It’s not known how long these antibodies will stick around in the blood or whether they can effectively block infection.

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Emily Mullin
Medium Coronavirus Blog

Former staff writer at Medium, where I covered biotech, genetics, and Covid-19 for OneZero, Future Human, Elemental, and the Coronavirus Blog.