Decoding Pfizer’s Covid-19 Vaccine Ingredients

People have started receiving doses of the BNT162b2 vaccine in the U.K. This article details the ingredients included in the vaccine.

Jesse Smith, MD
Medium Coronavirus Blog

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Image: Wikipedia commons

On December 8 a U.K. woman named Margaret Keenan became the first person to receive a Covid-19 vaccine. At age 90, Keenan marked the beginning of what will be a broad global effort to vaccinate people against Covid-19.

As doses make their way to the United States, this article details the ingredients included in Pfizer’s BNT162b2 vaccine.

The basics

BNT162b2, much like the vaccine being offered by Pfizer-BioNTech, is an mRNA vaccine made up of strands of RNA packed into lipid nanoparticles. These particles, when injected into the human body, will fuse to the cell membrane of human cells and allow the mRNA to gain access to the machinery needed to translate it into viral proteins. Once these proteins are generated, they are packaged and released outside of the cell.

Once the viral proteins are released, our immune system has the opportunity to generate antibodies against them.

Lipid nanoparticle technology

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Jesse Smith, MD
Medium Coronavirus Blog

Physician and molecular biologist. I write about topics in science and medicine that relate to everyone.